One of the key areas in pharmaceuticals is the precise targeting of drugs to selected cells or tissues. Drug targeting systems must control the fate of the drug entering the body. Today's delivery technologies are numerous, with the so-called "magic bullet" scheme proposed by Paul Ehrlich at the beginning of the 20th century, in which the drug is delivered precisely to the target. Nano drug delivery systems (NDDSs) are categories of nanomaterials that increase the stability and solubility of drugs in water, prolong the cycle time, increase the absorption rate of target cells or tissues, and reduce enzymes, thus improving safety. And drug efficacy NDDS can be administered through existing routes including inhalation, oral administration or intravenous injection and remains better bioavailability. Nanoparticles are classified as nanoparticles with a diameter between 10 and 100 nm. During the design of nanoparticles, some controls such as release patterns and surface properties should be taken into account, which, with an appropriate dosing scheme, determine the activation of specific sites at optimal rates. Many new carriers have been registered for implants in the last ten years, including nanosomes, nanophytosomes, nanoemulsions, transferosomes, and autosomes. The aim of this study is to synthesize various newly developed technologies for drug delivery of herbal medicines to improve therapeutic response.